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14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
Approximately 90% of all UTIs in young women arecaused by E. coli which is a gram-negative, rod-shaped bacterium and a memberof the normal intestinal microorganism.  The current study was conducted to determineantibiotic resistance and genotyping of uropathogenic E. coli strains isolatedfrom the patients with urinary tract infections in Tehran...ReadMore">


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
Obstructivenephropathy (ON) secondary to the congenital hydronephrosis (HN) is one of themost common causes of chronic kidney disease in children. Neither currentlyused imaging techniques nor conventional laboratory parameters are sufficientto assess the onset and outcome of this condition; hence, there is a need toprove the usefulness of newly discovered biomarkers of kidney injury in thisrespect. The purpose of the study was to assess the urinary excretion ofalpha-GST, pi-GST, NGAL, and KIM-1 and the serum level of NGAL in children withcongenital unilateral hydronephrosis secondary to ureteropelvic junctionobstruction. The results were evaluated in relation to severity of HN, thepresence of ON, relative function of an obstructed kidney, and the presence ofproteinuria...ReadMore">


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
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14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
kidney disease (CKD), as well as in CKD animalmodels, and kidney transplantdonors have a greater risk of end-stage renal disease than healthy controls. However,whether or not the intrarenal RAS is activated immediately after kidney donation in kidney transplant donors is unclear, andthe mechanism underlying intrarenal RAS activation is unknown.  The present study was performed to clarifywhether or not urinary plasma angiotensinogen (AGT) excretion, which reflectsthe intrarenal RAS, increases immediately after kidney donation in kidney transplantdonors who have no existing renal damage.  Also, investigated the factors associated withintrarenal RAS activation....ReadMore">


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
There is growing evidencethat nonalcoholic fatty liver disease (NAFLD) is associated with ahigher risk of urolithiasis, but it has not yet been determined that thisassociation is reproducible and consistent across different studies. Thepresent systematic review and meta-analysis investigated the association between NAFLD andthe risk of urolithiasis,representing a comprehensive assessment of this association to date. Thedata provide evidence suggesting an increased riskof urolithiasis among patients with NAFLD.... ReadMore">


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
Diabeticnephropathy (DN) is themajor cause of end-stage renal disease. Recent studies suggest that it isprobable that uric acid is involved in the pathogenesis of diabetic nephropathy. A case controlled study wasconducted to investigate the association between serum uric acid and kidneyfunction in Iranian patients with type 2 diabetes mellitus.ReadMore">


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
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The maternal and fetal Renin-Angiotensin-Systemis involved in the control of pregnancy outcomes such as blood pressure controland gestational age. However, very little is known about the impact of theangiotensin converting enzyme 2 (ACE2) on pregnancy outcome. A prospectiveclinical observational study was conducted to analyse the association ofmaternal and fetal ACE2 gene rs2074192 polymorphism with fetal growth duringpregnancyThis is the first study showing thatthe babies but not their mothers with ACE2 gene rs2074192 T allele had a highrisk for SGA, which contributes to metabolic syndrome andcardiovascular diseases in later life.ReadMore">


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
The addition of immunosuppression to supportivecare reduces proteinuria in a subset of patients withIgA nephropathy (IgAN) but is associated with an increased rate ofadverse events. The present study investigates whether urinary biomarkers areable to identify subjects who benefit from immunosuppression and to predict theprogression of disease in a sub-cohort of the STOP-IgAN trial.ReadMore">

Identifying MVP patients at high risk of sudden death

 

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Identifying MVP patients at high risk of sudden death

 

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