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MITRAL CLIP-FR trial concluded that in patients with severe secondary mitral regurgitation, ra.....

MITRAL CLIP-FR trial concluded that in patients with severe secondary mitral regurgitation, ra.....



13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Transientischemic attack (TIA) is an ischemic episode of neurologic dysfunctioncharacterized by a spontaneous clinical resolution of symptoms within 24 hours.Mechanisms of this remarkable recovery are not yet well understood. In patientswith permanent brain injury caused by a stroke cortical levels ofg-Aminobutyric acid (GABA) are decreased. In this study, authors aimed toinvestigate, whether similar alterations of cortical GABA are also present inpatients with TIA.ReadMore">


13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Dizziness, a common chiefcomplaint, has an extensive differential diagnosis that includes both benignand serious conditions. Emergency physicians must distinguish the majority ofpatients with self-limiting conditions from those with serious illnesses thatrequire acute treatment. This article presents a new approach to diagnosis ofthe acutely dizzy patient that emphasizes different aspects of the history toguide a focused physical examination with the goal of differentiating benignperipheral vestibular conditions from dangerous posterior circulation strokesin the emergency department.ReadMore

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13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Single-centerretrospective study was conducted to identify markers of hypocapnic cerebralhypoperfusion (HYCH) in patients with orthostatic intolerance (OI) withouttachycardia and without orthostatic hypotension. The study results concludedthat both HYCH and Postural tachycardia syndrome (POTS) patients havecomparable decrease in cerebral blood flow velocity (CBFv) which is due tovasoconstrictive effect of hypocapnia. Blood flow velocity monitoring canprovide an objective biomarker for HYCH in OI patients without tachycardia.ReadMore ">


13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Statusepilepticus (SE) is one of the most critical symptoms of encephalitis.Studies on early predictions of progression to super-refractory statusepilepticus (SRSE) and poor outcome in SE due toacute encephalitis are scarce. This study aims to investigate thevalues of neuroimaging and continuous electroencephalogram (EEG) in themultimodal prediction.ReadMore">


13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Primarycentral nervous system (CNS) germ cell tumors (GCT) are a heterogeneous groupof tumors that are still poorly understood. In North America, GCTs compriseapproximately 1% of primary brain tumors in pediatric and young adult patients.GCTs can occur as pure or mixed subtypes; they are divided into germinomas,which are the most common subtype, and non-germinomatous germ cell tumors(NGGCTs), which consist of approximately one-third of GCTs and includeteratomas, embryonal carcinomas, choriocarcinomas, and yolk sac tumors.  The current literature is reviewed to discussthe pathophysiology, clinical presentation, assessment and diagnosis,treatment, molecular biology, and prognosis of primary CNS GCTs.ReadMore">


12 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Tremor isa syndrome that indicates the abnormal state of the central nervous system,primarily in the motor brain regions. Analysis of tremor parametersprovide significant information about the changes in the body motion controland can be used as an objective index of the central nervous system state.Existing methods are aimed at the analysis of visible tremor based onthe use of different sensors.  Theauthors suggest an alternative approach based on the use of a tensometricsystem performing tremor measurements whenthe tremor appears on the background of voluntary isometric efforts.The key advantage of this approach is that it allows to determinethe tremor before its visible manifestation.ReadMore ">


12 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Multiplesclerosis (MS) is a chronic inflammatory demyelination disorder with animmune-mediated pathophysiology that affects the central nervous system (CNS).  Like other autoimmune conditions, it has apredilection for female gender. This suggests a gender bias and a possible hormonalassociation. Inflammation and demyelination are hallmarks of MS. The aim of thearticle is to review the available research on sex hormone-specific immunemodulatory effects, assess its remyelination potential in MS, and suggest afuture path for more extensive research on sex hormone as a target fortherapeutics in MS.ReadMore">


12 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Onethird of children with epilepsy are refractory to medications. Growing datasupport a role of common childhood infections with neurotropic viruses andinflammation in epileptogenesis. A cross-sectional multi-center study wasconducted to determine the frequency of Human Herpesvirus-6 (HHV-6) andEpstein-Barr Virus (EBV) infection and cytokine levels in saliva from childrenwith seizures compared to healthy controls and to controls with a febrileillness without seizures.ReadMore

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6 Nov | Categories : Endocrinology Start a topic Comment Mail Share Download
Patients with rheumatic diseases, such asrheumatoid arthritis (RA) and ankylosing spondylitis (AS), encountersignificantly higher rates of cardiovascular morbidity and mortality. Toinvestigate the levels of renin and aldosterone in RA and AS patients, threegroups were recruited, patients with RA, patients with AS, and healthycontrols.  Patients with RA tended tohave lower levels of plasma renin compared to healthy subjects. This findingindicates that the renin-angiotensin-aldosterone system might not be directlyinvolved in the process that results in increased cardiovascular events inrheumatoid arthritis.ReadMore">