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30 Oct | Categories : Nephrology Start a topic Comment Mail Share Download
biomarkers for predicting AKI has hampered the ability to take therapeutic measures for preventive cause.  A prospective diagnostic observational study of 51 children aged between 3 weeks and 12 years undergoing elective cardiac surgery in a tertiary care center was carried out to find out the role of serum phosphorus in prediction of AKI as a biomarker after cardiac surgery in children.ReadMore">
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30 Oct | Categories : Neurosurgery Start a topic Comment Mail Share Download
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30 Oct | Categories : Neurology Start a topic Comment Mail Share Download
synuclein (Lewy bodies). The movement disorder of PD occurs largely due to loss of dopaminergic neurons of the substantia nigra, resulting in striatal dopamine depletion. There are currently no proven disease modifying treatments for PD, with management options consisting mainly of dopaminergic drugs, and in a limited number of patients, deep brain stimulation. Long-term use of established dopaminergic therapies for PD results in significant adverse effects, and there is therefore a requirement to develop better means of restoring striatal dopamine, as well as treatments that are able to slow progression of the disease. Here, authors discuss the promising regenerative cell-based and gene therapies, designed to treat the dopaminergic aspects of PD whilst limiting adverse effects, as well as novel approaches to reducing ?-synuclein pathology.ReadMore">


30 Oct | Categories : Infectious Disease Start a topic Comment Mail Share Download
Abstract:  A prominent histopathological feature offatal dengue cases is hepatic steatosis. However, the association betweenhepatic steatosis and dengue severity is unknown. A retrospective study wasconducted to determine the associations of nonalcoholic fatty liver disease(NAFLD) with laboratory markers of dengue severity and length of hospital stay(LOS). ReadMore ">


30 Oct | Categories : Hematology Start a topic Comment Mail Share Download
Abstract:  The bone marrow microenvironment, also knownas the bone marrow niche, is a complex network of cell types and acellularfactors that supports normal hematopoiesis. Recent evidences have shown that acute myeloid leukemia cells induceosteogenic differentiation in mesenchymal stromal cells to gain a growthadvantage. This review discusses about the role of the osteogenic niche in themaintenance of hematopoietic stem and progenitor cells, as well as theirtransformation into leukemia cells. Also, discussed the signaling pathways thatregulate osteogenic nichehematopoietic stem and progenitor cells or osteogenicniche-leukemic stem/initiating cell interactions in the bone marrow, togetherwith novel approaches for therapeutically targeting these interactions.ReadMore

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30 Oct | Categories : Diabetology Start a topic Comment Mail Share Download
sulfonylurea, thiazolidinedione, or insulin) to treat patients with T2D.ReadMore">


30 Oct | Categories : Endocrinology Start a topic Comment Mail Share Download
Abstract: Overall, the current study demonstrated that vitamin D supplementationamong hypothyroid patients for 12 weeks improved serum TSH and calciumconcentrations compared with the placebo, but it did not alter serum T3, T4,ALP, PTH, and albumin levels. ReadMore">

Brum J, Ramsey D,  McRorie J,  Bauer B, Kopecky SL. Meta-Analysis of Usefulness of P.....

Brum J, Ramsey D,  McRorie J,  Bauer B, Kopecky SL. Meta-Analysis of Usefulness of P.....


Beddhu S, Chertow GM, Greene T, Whelton PK. Ambrosius WT, Cheung AK, et al. Effects of Intensi.....

Beddhu S, Chertow GM, Greene T, Whelton PK. Ambrosius WT, Cheung AK, et al. Effects of Intensi.....