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Oral diabetes medication monotherapy and short-term mortality in individuals with type 2 diabetes and coronary artery disease.


5 Nov | Categories : Diabetology Start a topic Comment Mail Share Download
Sulfonylurea use was common (nearly one-third ofthose taking medications) and was associated with increased 2-year mortality inindividuals with obstructive CAD. ReadMore">

Variables associated with HbA1c and weight reductions when adding liraglutide to multiple daily insulin injections in persons with type 2 diabetes (MDI Liraglutide trial 3)


5 Nov | Categories : Diabetology Start a topic Comment Mail Share Download
Weight reduction becomes greater when addingliraglutide in patients with type 2 diabetes treated with MDI who had a lowerHbA1c level compared with those with a higher HbA1c level.  There was no correlation between reductions inHbA1c and weight when liraglutide was added, that is, different patient groupsresponded with HbA1c and weight reductions.ReadMore">

Pioglitazone and cause-specific risk of mortality in patients with type 2 diabetes: extended analysis from a European multidatabase cohort study


5 Nov | Categories : Diabetology Start a topic Comment Mail Share Download
Describe and compare the risk of cardiovascularand non-cardiovascular mortality in patients whose antidiabetic therapy ismodified to include pioglitazone compared with an alternative antidiabeticmedication at the same stage of disease progression.Pioglitazone is associated with a decrease inboth cardiovascular and non-cardiovascular mortality.ReadMore">

Burden of Urological Complications in Men and Women With Long-standing Type 1 Diabetes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Cohor


5 Nov | Categories : Diabetology Start a topic Comment Mail Share Download
Type 1 diabetes has been associated with highrates of urinary and sexual problems, but the cumulative burden and overlap ofthese complications are unknown. We sought to determine prevalence ofurological complications in persons with type 1 diabetes, associations withclinical and diabetes-related factors, and rates of emergence, persistence, andremission. ReadMore">

Thrombosis and Vascular Inflammation in Diabetes: Mechanisms and Potential Therapeutic Targets.


5 Nov | Categories : Diabetology Start a topic Comment Mail Share Download
Abstract:  We address in this review thepathophysiological mechanisms responsible for atherosclerosis with specialemphasis on diabetes-related pathways. We also cover the enhanced thromboticmilieu, characterized by increased platelet activation, raised activity ofprocoagulant proteins together with compromised function of the fibrinolyticsystem. Potential new therapeutic targets to reduce the risk ofatherothrombosis in diabetes are explored, including alternative use ofexisting therapies.ReadMore

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SGLT2 Inhibitors in Combination Therapy: From Mechanisms to Clinical Considerations in Type 2 Diabetes Management.


5 Nov | Categories : Diabetology Start a topic Comment Mail Share Download
sulfonylurea, thiazolidinedione, or insulin) to treat patients with T2D.ReadMore">

Influenza updates 2018


2 Nov | Categories : Infectious Disease Start a topic Comment Mail Share Download
National Institute of communicable diseases in 2017 came up with the guidelines that recommend on the diagnosis, prevention and management of Influenza.

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Latest updates on Heart Failure


2 Nov | Categories : Cardiovascular Start a topic Comment Mail Share Download
European society of Cardiology released guidelines for diagnosis and management of patients with HF. Few excerpts to guide the doctors have been presented here.
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Microsurgical treatment of craniopharyngioma: Experiences on 183 consecutive patients


2 Nov | Categories : Neurosurgery Start a topic Comment Mail Share Download
Abstract: Craniopharyngioma is a type ofembryo-epithelium tumor which originates from the remnant tissue of Rathke’spouch, and the tumor mostly grows in saddle.[1–3] During growth, the tumor usuallyinfluences important tissue structures such as hypothalamus, visual pathway,stalk hypophysial and internal carotid. Besides, tumor removal may cause manycomplications, with low total removal and high recurrence rates. Thus, theresection of craniopharyngioma has always been a changeable operation inneurosurgery.  This study aimed tosummarize the clinical experiences and postoperative effects of microsurgicalapproaches for craniopharyngioma.ReadMore">

Impact of neutrophil-lymphocyte ratio on long-term outcome in patients with craniopharyngioma.


2 Nov | Categories : Neurosurgery Start a topic Comment Mail Share Download
Abstract: Neutrophil–lymphocyte ratio (NLR) is a poor prognostic factor inmany tumors including glioblastoma multiforme (GBM), colorectal, and prostatecancer. The study was conducted to investigate the prognostic values ofpreoperative NLR in patients with craniopharyngioma.  Preoperative NLR may be a simple, readilyavailable and valid predictor of long-term outcome in craniopharyngioma.  The study suggested that the NLR can provideeffective guidance to neurosurgeons for more information about the tumor andprognostic evaluation.ReadMore">