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Association of serum uric acid with nephropathy in Iranian type 2 diabetic patients.


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
Diabeticnephropathy (DN) is themajor cause of end-stage renal disease. Recent studies suggest that it isprobable that uric acid is involved in the pathogenesis of diabetic nephropathy. A case controlled study wasconducted to investigate the association between serum uric acid and kidneyfunction in Iranian patients with type 2 diabetes mellitus.ReadMore">

Cyst infection in autosomal dominant polycystic kidney disease: penetration of meropenem into infected cysts.


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
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Fetal But Not Maternal Angiotensin Converting Enzyme (ACE)-2 Gene Rs2074192 Polymorphism is Associated with Increased Risk of Being a Small For Gestational Age (SGA) Newborn.


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
The maternal and fetal Renin-Angiotensin-Systemis involved in the control of pregnancy outcomes such as blood pressure controland gestational age. However, very little is known about the impact of theangiotensin converting enzyme 2 (ACE2) on pregnancy outcome. A prospectiveclinical observational study was conducted to analyse the association ofmaternal and fetal ACE2 gene rs2074192 polymorphism with fetal growth duringpregnancy.  This is the first study showing thatthe babies but not their mothers with ACE2 gene rs2074192 T allele had a highrisk for SGA, which contributes to metabolic syndrome andcardiovascular diseases in later life.ReadMore">

Urinary Biomarkers in the Prediction of Prognosis and Treatment Response in IgA Nephropathy.


14 Nov | Categories : Nephrology Start a topic Comment Mail Share Download
The addition of immunosuppression to supportivecare reduces proteinuria in a subset of patients withIgA nephropathy (IgAN) but is associated with an increased rate ofadverse events. The present study investigates whether urinary biomarkers areable to identify subjects who benefit from immunosuppression and to predict theprogression of disease in a sub-cohort of the STOP-IgAN trial.ReadMore">

   Identifying MVP patients at high risk of sudden death

Identifying MVP patients at high risk of sudden death

 

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Identifying MVP patients at high risk of sudden death

 

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   Mitral Clip Conundrum

MITRAL CLIP-FR trial concluded that in patients with severe secondary mitral regurgitation, ra.....

MITRAL CLIP-FR trial concluded that in patients with severe secondary mitral regurgitation, ra.....


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Decreased GABA levels in the symptomatic hemisphere in patients with transient ischemic attack


13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Transientischemic attack (TIA) is an ischemic episode of neurologic dysfunctioncharacterized by a spontaneous clinical resolution of symptoms within 24 hours.Mechanisms of this remarkable recovery are not yet well understood. In patientswith permanent brain injury caused by a stroke cortical levels ofg-Aminobutyric acid (GABA) are decreased. In this study, authors aimed toinvestigate, whether similar alterations of cortical GABA are also present inpatients with TIA.ReadMore">

A New Diagnostic Approach to the Adult Patient with Acute Dizziness.


13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Dizziness, a common chiefcomplaint, has an extensive differential diagnosis that includes both benignand serious conditions. Emergency physicians must distinguish the majority ofpatients with self-limiting conditions from those with serious illnesses thatrequire acute treatment. This article presents a new approach to diagnosis ofthe acutely dizzy patient that emphasizes different aspects of the history toguide a focused physical examination with the goal of differentiating benignperipheral vestibular conditions from dangerous posterior circulation strokesin the emergency department.ReadMore

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Hypocapnic cerebral hypoperfusion: A biomarker of orthostatic intolerance.


13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Single-centerretrospective study was conducted to identify markers of hypocapnic cerebralhypoperfusion (HYCH) in patients with orthostatic intolerance (OI) withouttachycardia and without orthostatic hypotension. The study results concludedthat both HYCH and Postural tachycardia syndrome (POTS) patients havecomparable decrease in cerebral blood flow velocity (CBFv) which is due tovasoconstrictive effect of hypocapnia. Blood flow velocity monitoring canprovide an objective biomarker for HYCH in OI patients without tachycardia.ReadMore ">

Multimodal Predictions of Super-Refractory Status Epilepticus and Outcome in Status Epilepticus Due to Acute Encephalitis.


13 Nov | Categories : Neurology Start a topic Comment Mail Share Download
Statusepilepticus (SE) is one of the most critical symptoms of encephalitis.Studies on early predictions of progression to super-refractory statusepilepticus (SRSE) and poor outcome in SE due toacute encephalitis are scarce. This study aims to investigate thevalues of neuroimaging and continuous electroencephalogram (EEG) in themultimodal prediction.ReadMore">