MI with AF – a Dilemma for Antithrombotics

Mar 15 2019 , India
POWAI

Key Points:

  1. Outcomes of antithrombotic regimes were compared in consecutive patients with myocardial infarction (MI) and atrial fibrillation (AF).
  2. Aspirin or clopidogrel plus warfarin was associated with a similar 0–90 days and a lower 91–365 days of risk of the composite of mortality, MI, or ischaemic stroke compared with dual antiplatelet therapy (DAPT), without increased risk of major bleeds. Triple therapy was associated with a similar risk of the composite of mortality, MI, or ischaemic stroke, but with an almost double the risk of major bleeds requiring in-hospital attention than dual antiplatelet therapy.

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